థ్రెయోనిన్ డీమినేస్

వివరణ:

L-2-aminobutyric acid (L-ABA) is a non-natural chiral amino acid and has a wide range of applications in the fields of medicine and chemical industry. The system for synthesizing L-ABA by leucine dehydrogenase is based on L-threonine, which is deaminated by threonine deaminase to form α-ketobutyrate, and then ketone is used to remove ketone. The acid is reduced to L-ABA while the NADH consumed by the reduction reaction is regenerated by formate dehydrogenase. The preparation of L-2-aminobutyric acid in this production system has a problem that the consumption of coenzyme is excessively large, and thus coenzyme regeneration can be completed by formate dehydrogenase.

అప్లికేషన్లు:

This enzyme is used to prepare L-2-aminobutyric acid by enzymatic method.